Do Skin Rejuvenation Treatments Work? What Clinical Studies Show

With countless aesthetic treatments on the market and promises of younger, firmer skin everywhere you turn, it's fair to ask—do skin rejuvenation treatments actually work? And more importantly, what does science say?

At Rosem Health in West Bridgford, we specialise in advanced skin rejuvenation treatments backed by evidence—not hype. In this post, we’ll explore the real clinical research behind popular non-surgical treatments like laser resurfacing, chemical peels, radio-frequency, LED therapy, and HIFU. Whether you're considering treatment for fine lines, pigmentation, sagging skin or acne scars, we’ll help you understand what works and why.

What Is Skin Rejuvenation?

Skin rejuvenation refers to a variety of non-invasive or minimally invasive aesthetic procedures aimed at restoring youthful skin tone, texture, firmness, and clarity. These treatments target common signs of ageing and skin damage caused by sun exposure, environmental stressors, and hormonal changes.

At Rosem Health, our skin rejuvenation options include:

• Fractional CO2 laser resurfacing

• Chemical peels (Glo Skin Beauty Peels)

• Radio-frequency (RF) tightening

• LED light therapy

• HIFU (High-Intensity Focused Ultrasound)

• Medical micro-needling

  
  

1. Laser Resurfacing: Evidence for Wrinkle Reduction & Collagen Boost

Laser treatments, particularly fractional CO2 lasers, are widely recognised as one of the most effective non-surgical options for reducing wrinkles, pigmentation and improving skin tone.

The Science:

A 2016 review in Dermatologic Surgery found that fractional laser treatments significantly increase collagen production, with noticeable improvements in fine lines and skin texture after just 2–3 sessions (Tanzi et al., 2016).

Another clinical trial published in Lasers in Medical Science (2020) concluded that fractional CO2 laser therapy led to a 20–45% improvement in wrinkle severity and skin elasticity over 12 weeks.

What it’s best for: Deep wrinkles, sun damage, acne scars, uneven tone and texture.

2. Chemical Peels: Clinically Proven Skin Renewal

Chemical peels use acids to exfoliate the skin’s surface, revealing fresher, clearer skin and stimulating new cell growth.

The Science:

A clinical study in the Journal of Clinical and Aesthetic Dermatology (2018) showed that glycolic and salicylic acid peels significantly reduced acne lesions and improved hyperpigmentation within 4–6 weeks.

Lactic acid and mandelic acid peels, like those used in our Glo Skin Beauty range, have been found to increase dermal thickness and reduce fine lines without aggressive downtime (Kligman et al., 1996).

What it’s best for: Mild-to-moderate ageing signs, pigmentation, acne, dullness, uneven texture.

3. Radio-Frequency (RF) Treatments: Collagen Stimulation Without Downtime

RF skin tightening works by delivering heat deep into the dermis to stimulate collagen and elastin, improving firmness and reducing laxity.

The Science:

A 2017 study published in Dermatologic Therapy demonstrated that bipolar RF devices improved skin laxity in 80% of patients after 4 sessions, with increased collagen fibres observed on biopsy.

RF is particularly suitable for mild-to-moderate sagging skin in the face, jawline and neck—often where surgery would previously be considered.

What it’s best for: Skin tightening, jawline definition, early signs of sagging.

4. LED Therapy: Low-Level Light That Delivers Results

LED light therapy uses red, blue, or near-infrared light to stimulate skin healing, reduce inflammation and promote collagen production.

The Science:

A systematic review published in Seminars in Cutaneous Medicine and Surgery (2013) found that red and near-infrared LED light significantly improved fine lines, skin roughness, and overall skin appearance, especially when used regularly.

Blue light is particularly effective for acne-prone skin due to its antibacterial properties against Propionibacterium acnes, while red light helps reduce inflammation and stimulate repair.

What it’s best for: Acne, inflammation, post-treatment healing, dull skin.

5. HIFU (High-Intensity Focused Ultrasound): The Non-Surgical Facelift (and Body)

HIFU is a revolutionary non-invasive procedure that delivers ultrasound energy below the skin to trigger deep tissue regeneration and collagen formation.

The Science:

A 2015 study in The Journal of Clinical and Aesthetic Dermatology followed patients receiving HIFU treatment for facial rejuvenation. After 90 days, 89% of participants showed measurable lifting and tightening, particularly around the jawline and neck.

It’s the closest non-surgical alternative to a facelift—ideal for those not ready for more invasive options.

What it’s best for: Skin lifting, jawline sculpting, neck tightening.

So... Do Rejuvenation Treatments Really Work?

Yes—when performed correctly and selected based on your skin’s unique needs, rejuvenation treatments can be incredibly effective. Clinical evidence consistently supports the results seen with fractional lasers, chemical peels, RF, HIFU, and LED.

But the key to long-lasting improvement lies in consistency, expert guidance, and a personalised treatment plan.

At Rosem Health in West Bridgford, our practitioners are clinically trained to assess your skin concerns and recommend a treatment pathway that delivers visible results—without gimmicks or unrealistic promises.

Common Concerns & FAQs

How many treatments will I need? Most treatments require a course of 3–6 sessions for best results, depending on your skin goals and the modality used.

Is it painful? Most treatments are very tolerable with only mild discomfort. For more intensive treatments like CO2 laser, topical numbing is applied.

Will I need downtime? Downtime varies. LED and RF require no downtime, while peels or CO2 laser may involve mild redness or flaking for a few days.

Are the results permanent? Skin ageing continues naturally, but these treatments slow the process and improve your baseline, especially when combined with healthy lifestyle habits and ongoing maintenance.

Take the First Step Toward Healthier, Younger-Looking Skin

If you're ready to experience skin rejuvenation that’s backed by science and delivered with care, Rosem Health is here to help.

Whether you're concerned about wrinkles, pigmentation, or skin sagging—we’ll recommend a personalised plan using the most effective, evidence-based treatments available.

📍 Visit us in West Bridgford or book a consultation online to get started.

📞 Have questions? Contact us at info@rosem.co.uk